by Denise Nichols, Staff Writer
Gulf War illness researchers UK’s Malcom Hooper (Professor of medicinal chemistry at the UK’s Sunderland University) and US’s Researcher Professor Mohamed Abou-Donia (a specialist in neurotoxicity from Duke University in North Carolina) along with University of Washington professor Clement Furlong have been making headway on identifying biomarkers that will be important for Aircrew members and suspectible passengers on commerical airliners. In addition the military aircrews and passengers they fly might also keep up with this landmark scientific work.
The scientific work is identifying blood markers in the blood of air crew and passengers that would link neurological degeneration to exposure to cabin air that has been contaminated by neurotoxic organophosphates from engine oil.
This involves bleed air contamination from fumes in the cabin from neurotoxic organophosphates from engine oil that can cause MS like symptoms and multiple chemical sensitivity symptoms, and that feeling of chronic fatigue that one might get after a long flight blaming it on partial pressure oxygenation, altitude physiologic effects, and lack of blood flow in extremities after long flights.
This scientific work will nicely dovetail into Gulf War illness research involving contaminations with organophosphates and combinations of environmental exposures ie pesticides/sarin in theater during the gulf war One must also consider pesticides used in international flights both civilian and military to decrease the pests that come on board in austere locations like the desert.
WE do indeed have complex environmental exposures. The effects are neurotoxic but when you are dealing with neurotoxin one can not negate psychological symptoms that may occur secondary to those exposures or further worsen the severity of those symptoms from PTSD. It is also too soon in this research process to rule out other diagnosed illnesses involving cardiac and other organ diseases when the autonomic nervous system is probably involved and is showing dysfunction or dysregulation.
This is truly the cutting edge research that our governments should be fully funding to get answers for military, veterans, and civilians alike.
Further correlation is needed re engine oil used in airlines and military equipment.
DATE:01/05/09
SOURCE:Flight International
US researcher nears cabin contamination blood marker breakthrough
By David Learmount
A US medical researcher is "just months away" from identifying blood markers in the blood of air crew and passengers that would link neurological degeneration to exposure to cabin air that has been contaminated by neurotoxic organophosphates from engine oil.
Delegates to the 28-29 April meeting in London of the Global Cabin Air Quality Executive (GCAQE) concluded that the commercial air transport industry would have to take radical action to deal with the health effects of bleed air contamination incidents. They had heard University of Washington professor Clement Furlong explain that "biomarkers" he is studying in the blood of crew and passengers who have suffered neurological degeneration after flying will scientifically link cabin fume events to his patients’ medical condition.
The industry has not contested the fact that organophosphates can cause neurological damage, but it has successfully argued, so far, that the cabin air events cannot be linked to the symptoms of the crew and passengers.
Also at the GCAQE meeting, the National Institute of Occupational Health in Norway reported it has issued 10 portable testers to crews so that if they suspect a contamination event they can activate the devices, which run for 30min to collect evidence.
In addition, Professor Mohamed Abou-Donia, a specialist in neurotoxicity from Duke University in North Carolina, said people suffering from toxic cabin air are sometimes misdiagnosed as having multiple sclerosis. Professor of medicinal chemistry at the UK’s Sunderland University, Dr Malcolm Hooper, said "multiple chemical sensitivity" effects on human neurology, such as the now-recognised Gulf War Syndrome, are much more complex than the sum of the effects of the individual chemicals.
Finally the Australian Civil Aviation Safety Authority, which has assembled an "expert panel on aircraft air quality" expects to provide scientific conclusions early in 2010.
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